Description

Mono-(6-(Diethylenetriamine)-6-Deoxy)-β-Cyclodextrin is a chemically modified cyclodextrin derivative where a single primary hydroxyl group on the β-cyclodextrin scaffold is replaced with a diethylenetriamine moiety. This functionalization imparts unique properties, making it a valuable host molecule and chiral selector for complexation and separation science. It is primarily utilized in pharmaceutical research, analytical chemistry, and catalysis for enantiomeric separation, drug delivery, and as a supramolecular catalyst.

Application

• Chiral Stationary Phases (CSPs): A key component in high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) columns for the separation of enantiomers in pharmaceutical intermediates and active ingredients.
• Drug Delivery Systems: Acts as a functional carrier to improve the solubility, stability, and targeted delivery of poorly water-soluble active pharmaceutical ingredients (APIs).
• Supramolecular Catalysis: Serves as an enzyme-mimetic catalyst or a nanoreactor in organic synthesis due to its well-defined cavity and amine-functionalized arm.
• Chemical Sensors and Biosensors: Used as a recognition element in sensor design for the selective detection of specific ions, molecules, or biomolecules.
• Protein and Enzyme Studies: Employed as a tool to study protein-ligand interactions, protein folding, and enzyme inhibition.
• Environmental Analysis: Applied in sample preparation and extraction techniques for the pre-concentration and separation of environmental pollutants.

Basic Information

Product Name	Mono-(6-(Diethylenetriamine)-6-Deoxy)-β-Cyclodextrin
CAS No.	65294-32-8
Molecular Formula	C50H88N4O34
Molecular Weight	~1281.24 g/mol
Synonyms	6A-Diethylenetriamino-6A-deoxy-β-cyclodextrin; 6-Mono(diethylenetriamino)-6-deoxy-β-cyclodextrin; β-CD-DETA; Mono-6-deoxy-6-diethylenetriamino-β-cyclodextrin; 6-Diethylenetriamine-β-cyclodextrin; Amino-functionalized β-cyclodextrin; DETA-β-CD; 6I-Amino-6I-deoxy-β-cyclodextrin derivative
EINECS	Contact for details

Quality Control

Our Mono-(6-(Diethylenetriamine)-6-Deoxy)-β-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and structural confirmation via NMR and MS, to ensure it meets the high standards required for research and analytical applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.