Description

Hexane-1-Sulphonyl Fluoride is a specialized organosulfur compound featuring a reactive sulphonyl fluoride group on a hexyl chain. This chemical is a valuable intermediate and reagent in advanced organic synthesis, particularly for introducing sulphonamide functionalities. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials. Its unique reactivity profile makes it essential for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel sulphonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with sulphonamide moieties.
• Chemical Biology & Proteomics: Acts as a reactive probe in activity-based protein profiling (ABPP) to label and study serine hydrolases and other enzymes.
• Material Science: Intermediate for creating specialized polymers, surfactants, or surface-modifying agents with specific sulfonyl fluoride reactivity.
• Cross-coupling Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for carbon-sulfur bond formation.
• Fluorination Agent: Serves as a source of fluorine in selective fluorination reactions under controlled conditions.

Basic Information

Product Name	Hexane-1-Sulphonyl Fluoride
CAS No.	65269-96-7
Molecular Formula	C₆H₁₃FO₂S
Molecular Weight	168.23 g/mol
Synonyms	1-Hexanesulfonyl fluoride; n-Hexanesulfonyl fluoride; Hexylsulfonyl fluoride; NSC 405124; 1-Hexylsulfonyl fluoride; Hexane-1-sulfonyl fluoride; n-Hexylsulfonyl fluoride
EINECS	Contact for details

Quality Control

Our Hexane-1-Sulphonyl Fluoride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Use appropriate explosion-proof equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.