Description

3-Amino-2-Chloro-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and chloro-substituted pyridine core. This compound matters as a critical intermediate for synthesizing advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced properties.

Application

This versatile chemical intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorine-containing motifs for improved bioavailability and target binding.
• Agrochemical Active Ingredient Development: Building block for next-generation herbicides, insecticides, and fungicides, leveraging the biological activity of the pyridine and trifluoromethyl groups.
• Ligand Synthesis for Catalysis: Preparation of specialized nitrogen-containing ligands used in homogeneous catalysis and material science.
• Functional Material Research: Intermediate in the development of advanced organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services catering to specific client R&D projects.

Basic Information

Product Name	3-Amino-2-Chloro-6-(Trifluoromethyl)Pyridine
CAS No.	65182-56-1
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	2-Chloro-3-amino-6-(trifluoromethyl)pyridine; 3-Amino-2-chloro-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-pyridinamine, 2-chloro-; 2-Chloro-6-(trifluoromethyl)pyridin-3-amine; 2-Chloro-3-pyridinamine, 6-(trifluoromethyl)-; 3-Pyridinamine, 2-chloro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloro-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.