Description

Benzyloxycarbonylphenylalanylphenylalanine Diazomethyl Ketone is a specialized, high-purity synthetic peptide derivative designed for advanced research and development applications. This compound serves as a critical building block and a potent, irreversible inhibitor of serine proteases, enabling precise biochemical studies and pharmaceutical development. It is essential for researchers and manufacturers in the fields of protease inhibitor design, peptide chemistry, and drug discovery, particularly for investigating enzyme mechanisms and developing therapeutic agents.

Application

• Protease Inhibitor Research: Acts as a potent, mechanism-based irreversible inhibitor for studying serine proteases like chymotrypsin, elastase, and related enzymes.
• Pharmaceutical Intermediate: Serves as a key synthetic intermediate in the development of novel peptide-based therapeutic agents and protease-targeting drugs.
• Biochemical Tool Compound: Used in enzymology labs to probe active sites, study enzyme kinetics, and understand inhibition pathways.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis as a protected dipeptide derivative for constructing larger, complex peptide sequences.
• Academic & Industrial R&D: A vital reagent for universities, research institutes, and biotech companies focused on protein biochemistry and medicinal chemistry.

Basic Information

Product Name	Benzyloxycarbonylphenylalanylphenylalanine Diazomethyl Ketone
CAS No.	65178-14-5
Molecular Formula	C27H25N3O5
Molecular Weight	471.51 g/mol
Synonyms	Z-Phe-Phe-CHN2; Cbz-Phe-Phe-diazomethyl ketone; Z-Phe-Phe-CHN2; Benzyloxycarbonyl-L-phenylalanyl-L-phenylalanine diazomethyl ketone; Z-Phe-Phe diazomethyl ketone; (Benzyloxycarbonyl)phenylalanylphenylalanine diazomethyl ketone; Protease Inhibitor Z-Phe-Phe-CHN2; Chymotrypsin Inhibitor Z-Phe-Phe-CHN2
EINECS	Contact for details

Quality Control

Our Benzyloxycarbonylphenylalanylphenylalanine Diazomethyl Ketone is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets the stringent requirements of pharmaceutical and biochemical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is strictly light-sensitive and hygroscopic; it must be handled in a dry, controlled environment and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.