Description

1-(1-Bromoethyl)-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on an ethylbenzene core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The benzyl bromide moiety is highly reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for carbon-carbon bond formation.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and introducing the fluorinated phenethyl group into target molecules.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific halogenated aromatic frameworks.

Basic Information

Product Name	1-(1-Bromoethyl)-4-Fluorobenzene
CAS No.	65130-46-3
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-(1-Bromoethyl)-4-fluorobenzene; 4-Fluoro-α-bromoethylbenzene; 1-Bromo-1-(4-fluorophenyl)ethane; (1-Bromoethyl)-4-fluorobenzene; p-Fluoro-α-bromoethylbenzene; 4-Fluorophenethyl bromide; α-Bromo-4-fluoroethylbenzene; 1-(4-Fluorophenyl)ethyl bromide
EINECS	Contact for details

Quality Control

Our 1-(1-Bromoethyl)-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.