Description

Ent-Pge2 CAS NO 65085-69-0 is a high-purity enantiomer of Prostaglandin E2, a key bioactive lipid mediator. This specific stereoisomer is crucial for advanced pharmacological research and development, offering precise biological activity for targeted studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on inflammation, reproductive biology, and oncology pathways.

Application

• Pharmacological Research: Used as a reference standard and active agent in studying prostaglandin receptor (EP1-4) signaling and function.
• Drug Discovery & Development: Serves as a critical intermediate or biological tool compound in the development of novel anti-inflammatory and cytoprotective therapeutics.
• Cell Biology Studies: Employed to investigate cellular processes such as smooth muscle contraction, immune modulation, and angiogenesis in controlled experimental models.
• Biochemical Assay Development: Acts as a high-purity calibrant and control in developing ELISA, radioimmunoassay (RIA), and other analytical methods for eicosanoid quantification.
• Academic Research: Supports fundamental research in physiology and pathology related to pain, fever, fertility, and gastrointestinal function.

Basic Information

Product Name	Ent-Pge2
CAS No.	65085-69-0
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	(-)-PGE2; ent-Prostaglandin E2; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; 9-Oxo-11α,15S-dihydroxy-(5Z,13E)-prostadienoic acid; PGE2 enantiomer; 15S-PGE2; Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11α,13E,15S)-
EINECS	Contact for details

Quality Control

Our Ent-Pge2 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.