Description

2-Pyridyl Trifluoromethanesulfonate is a high-purity, versatile triflate ester reagent essential for advanced organic synthesis. This compound serves as a critical building block for introducing the 2-pyridyl moiety into complex molecular architectures via cross-coupling and nucleophilic substitution reactions. It is particularly valuable for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for constructing heterocyclic compounds and kinase inhibitors.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides by serving as a precursor for pyridine-containing bioactive molecules.
• Ligand and Catalyst Preparation: Essential for synthesizing sophisticated pyridyl-based ligands used in homogeneous catalysis and coordination chemistry.
• Material Science: Building block for organic electronic materials, including charge-transport layers and light-emitting compounds.
• Cross-Coupling Reactions: Excellent electrophile in Suzuki-Miyaura, Stille, and Negishi cross-coupling reactions to form biaryl and heteroaryl systems.
• Nucleophilic Substitution: Reactive substrate for nucleophilic aromatic substitution with various amines, alkoxides, and thiols.

Basic Information

Product Name	2-Pyridyl Trifluoromethanesulfonate
CAS No.	65007-00-3
Molecular Formula	C7H4F3NO3S
Molecular Weight	239.17 g/mol
Synonyms	2-Pyridyl Triflate; Pyridin-2-yl Trifluoromethanesulfonate; 2-(Trifluoromethanesulfonyloxy)pyridine; 2-Pyridyloxy Triflate; Trifluoromethanesulfonic Acid 2-Pyridyl Ester; 2-PyOTf; 2-Pyridinol, Triflate
EINECS	Contact for details

Quality Control

Our 2-Pyridyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.