Description

5-Bromopyridine-3-Sulfonyl Chloride is a versatile and highly reactive organic intermediate, primarily valued for its role as a key building block in the synthesis of more complex molecules. Its sulfonyl chloride functional group makes it an essential reagent for introducing the sulfonamide moiety, a critical pharmacophore in medicinal chemistry. This compound is particularly sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors, receptor antagonists, and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the sulfonamide group enhances biological activity.
• Material Science Research: Serves as a building block for creating functionalized polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector with tailored, high-purity compounds.

Basic Information

Product Name	5-Bromopyridine-3-Sulfonyl Chloride
CAS No.	65001-21-0
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.50 g/mol
Synonyms	3-Bromo-5-chlorosulfonylpyridine; 5-Bromo-3-pyridinesulfonyl chloride; 3-Pyridinesulfonyl chloride, 5-bromo-; 5-Bromopyridine-3-sulphonyl chloride; 65001-21-0; 5-Br-Py-3-SO2Cl
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.