Description

(5Z,13E,15S)-6,9α-Epithio-11α,15-Dihydroxyprosta-5,13-Dien-1-Oic Acid CAS NO 64868-63-9 is a specialized prostaglandin analog, a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its unique epithio and dihydroxy structural features, which are critical for modulating biological activity in targeted therapeutic pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel anti-inflammatory, cardiovascular, and ophthalmic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and active probe in studies of prostaglandin receptors and signaling pathways.
• Drug Discovery: Employed in high-throughput screening and structure-activity relationship (SAR) studies for new drug candidates.
• Anti-inflammatory Agent Development: Investigated for its potential in creating new treatments for inflammatory conditions.
• Ophthalmic Drug Synthesis: A precursor in the development of prostaglandin analogs used to treat glaucoma.
• Cardiovascular Research: Utilized in research exploring the role of prostaglandins in vascular tone and platelet aggregation.

Basic Information

Product Name	(5Z,13E,15S)-6,9α-Epithio-11α,15-Dihydroxyprosta-5,13-Dien-1-Oic Acid
CAS No.	64868-63-9
Molecular Formula	C₂₀H₃₀O₅S
Molecular Weight	382.52 g/mol
Synonyms	6,9α-Epithio-11α,15-dihydroxyprosta-5,13-dien-1-oic acid; 11α,15-Dihydroxy-6,9α-epithioprosta-5,13-dien-1-oic acid; 6,9α-Epithio-PGF₁α; Epithioprostaglandin F1α analog; SQ 28,603; SQ-28603; 6,9α-Epithio-11α,15-dihydroxy-(5Z,13E)-prostadienoic acid
EINECS	Contact for details

Quality Control

Our production of (5Z,13E,15S)-6,9α-Epithio-11α,15-Dihydroxyprosta-5,13-Dien-1-Oic Acid adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.