Description

3-Chloro-4-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a sulfonyl chloride and a nitro-chloro substituted aromatic ring, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antibacterial agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the sulfonamide moiety contributes to biological activity.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating azo dyes and other complex colorants.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Chemical Research & Development: A valuable reagent for introducing the 3-chloro-4-nitrobenzenesulfonyl group into target molecules in medicinal and material science research.
• Ligand and Catalyst Preparation: Utilized in the design of novel ligands for metal catalysis and other advanced chemical processes.

Basic Information

Product Name	3-Chloro-4-Nitrobenzenesulfonyl Chloride
CAS No.	64835-30-9
Molecular Formula	C6H3Cl2NO4S
Molecular Weight	256.06 g/mol
Synonyms	4-Nitro-3-chlorobenzenesulfonyl chloride; 3-Chloro-4-nitrobenzene-1-sulfonyl chloride; 1-Chloro-2-nitro-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-chloro-4-nitro-; NSC 403119; 3-Chloro-4-nitrobenzenesulphonyl chloride; 3-Chloro-4-nitro-phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Nitrobenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and amines.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.