Description

(3E,5E)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-4-Phenoxy-3-Hydroxy-1-Butenyl]Cyclopentan-1α-Yl]-3,5-Heptadienoic Acid Methyl Ester is a high-purity synthetic prostaglandin intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex bioactive molecules, particularly those targeting specific receptor pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Key Intermediate in Prostaglandin Synthesis: Serves as a crucial precursor in the multi-step synthesis of prostaglandin analogs and related eicosanoids.
• Pharmaceutical Research & Development: Used in the discovery and development of new drugs targeting inflammation, cardiovascular function, and reproductive health.
• Biochemical Tool Compound: Employed in academic and industrial research to study prostaglandin receptor interactions and signaling pathways.
• Fine Chemical Manufacturing: Utilized in the controlled, large-scale production of high-value active pharmaceutical ingredients (APIs) for clinical trials and commercial use.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(3E,5E)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-4-Phenoxy-3-Hydroxy-1-Butenyl]Cyclopentan-1α-Yl]-3,5-Heptadienoic Acid Methyl Ester
CAS No.	64812-77-7
Molecular Formula	C25H32O6
Molecular Weight	428.52 g/mol
Synonyms	Methyl (3E,5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,R)-4-phenoxy-3-hydroxybut-1-en-1-yl]cyclopentyl]hepta-3,5-dienoate; Prostaglandin F2α Methyl Ester Derivative; 7-[3,5-Dihydroxy-2-(4-phenoxy-3-hydroxy-1-butenyl)cyclopentyl]-3,5-heptadienoic Acid Methyl Ester; PGF2α Analogue Intermediate; 64812-77-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (3E,5E)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-4-Phenoxy-3-Hydroxy-1-Butenyl]Cyclopentan-1α-Yl]-3,5-Heptadienoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry, cool, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.