Description

Benzo(A)Pyrenyl-1-Sulfate is a sulfate ester derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene, a key metabolite used in biochemical and toxicological research. This compound is essential for studying the metabolic activation pathways of environmental carcinogens and their subsequent DNA adduct formation. It serves as a critical analytical standard and research reagent for scientists in environmental toxicology, cancer research, and analytical chemistry laboratories worldwide.

Application

• Biochemical Research Standard: Used as a high-purity reference standard for calibrating analytical instruments in metabolic studies.
• Toxicology & Carcinogenesis Studies: Critical for investigating the metabolic activation of benzo[a]pyrene and the role of sulfate conjugation in its carcinogenicity.
• DNA Adduct Analysis: Employed in studies to understand and quantify the formation of specific DNA adducts, a key mechanism in chemical carcinogenesis.
• Enzyme Activity Assays: Serves as a substrate for studying the activity of sulfotransferase enzymes (SULTs) in vitro.
• Environmental Exposure Biomarker Development: Used in the development and validation of analytical methods to detect and quantify human exposure to polycyclic aromatic hydrocarbons (PAHs).
• Pharmaceutical Metabolism Research: Aids in understanding sulfate esterification pathways relevant to drug metabolism and detoxification.

Basic Information

Product Name	Benzo(A)Pyrenyl-1-Sulfate
CAS No.	64810-99-7
Molecular Formula	C20H12O4S
Molecular Weight	348.37 g/mol
Synonyms	Benzo[a]pyren-1-yl sulfate; 1-Hydroxybenzo[a]pyrene sulfate ester; BP-1-Sulfate; 1-Sulfoxybenzo[a]pyrene; Benzo(a)pyrene-1-sulfate; B[a]P-1-Sulfate; 1-BP Sulfate; Benzo[a]pyrene 1-sulfate
EINECS	Contact for details

Quality Control

Every batch of Benzo(A)Pyrenyl-1-Sulfate is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.