Description

4-(Fluoromethyl)-Benzaldehyde is a versatile aromatic aldehyde building block characterized by a reactive formyl group and a fluoromethyl substituent. This unique structure makes it a valuable intermediate for introducing fluorinated motifs into target molecules, enhancing their metabolic stability and lipophilicity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with improved environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Incorporation into specialty polymers to alter surface properties, stability, and performance.
• Cross-Coupling Reactions: The aldehyde group facilitates Suzuki, Heck, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring the effects of fluorine in organic molecules.

Basic Information

Product Name	4-(Fluoromethyl)-Benzaldehyde
CAS No.	64747-66-6
Molecular Formula	C8H7FO
Molecular Weight	138.14 g/mol
Synonyms	p-(Fluoromethyl)benzaldehyde; 4-Fluoromethylbenzaldehyde; α-Fluoro-p-tolualdehyde; (4-Fluoromethyl)benzaldehyde; 1-Fluoromethyl-4-formylbenzene; Benzaldehyde, 4-(fluoromethyl)-; p-Fluoromethylbenzaldehyde; TOLUALDEHYDE, α-FLUORO-P-
EINECS	Contact for details

Quality Control

Our 4-(Fluoromethyl)-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to prevent oxidation. Keep away from strong acids and incompatible materials. For long-term storage, consider refrigeration (2-8°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.