Description

5-Quinolinesulfonylchloride,8-Hydroxy-(9Ci) is a specialized sulfonyl chloride derivative of hydroxyquinoline, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key sulfonylation reagent and intermediate in the development of complex molecules with targeted biological activities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes where the quinoline sulfonamide moiety is a privileged scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its bioactive quinoline core.
• Material Science Research: Employed in the creation of novel organic ligands for catalysis or functional materials due to its reactive sulfonyl chloride group and chelating hydroxy group.
• Bioconjugation Chemistry: Acts as a reagent for modifying biomolecules (e.g., proteins, peptides) by sulfonamide bond formation, useful in probe and therapeutic agent development.
• Dye and Pigment Intermediate: Serves as a building block for synthesizing complex heterocyclic dyes and functional colorants.

Basic Information

Product Name	5-Quinolinesulfonylchloride,8-Hydroxy-(9Ci)
CAS No.	64641-92-5
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	8-Hydroxy-5-quinolinesulfonyl chloride; 5-Quinolinesulfonyl chloride, 8-hydroxy-; 8-Hydroxyquinoline-5-sulfonyl chloride; 5-(Chlorosulfonyl)-8-hydroxyquinoline; 8-Hydroxy-5-sulfonylchloride quinoline; 8-Hydroxyquinoline-5-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Quinolinesulfonylchloride,8-Hydroxy-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics is provided with every shipment to guarantee it meets your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.