Description

19(R)-Hydroxy Prostaglandin E2 is a specialized prostaglandin analog, a key intermediate and reference standard in advanced biochemical research and pharmaceutical development. Its significance lies in its role as a potent bioactive lipid mediator for studying inflammatory pathways, cellular signaling, and receptor interactions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors focused on developing novel therapeutics and diagnostic tools.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and validation of analytical methods in drug development.
• Biochemical Research: Serves as a critical tool for investigating the role of prostaglandins in inflammation, pain, fever, and other physiological processes.
• Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel therapeutic agents targeting prostaglandin receptors.
• Cell Signaling Studies: Utilized in vitro and in vivo to study EP receptor-mediated signaling cascades and their effects on cellular function.
• Metabolite Analysis: Employed as an analytical standard in mass spectrometry and chromatography for the quantification of prostaglandin metabolites in biological samples.
• Academic & Institutional Research: Supports fundamental research in universities and research institutes exploring lipidomics, endocrinology, and reproductive biology.

Basic Information

Product Name	19(R)-Hydroxy Prostaglandin E2
CAS No.	64625-54-3
Molecular Formula	C₂₀H₃₄O₆
Molecular Weight	370.48 g/mol
Synonyms	19(R)-OH PGE2; 19R-Hydroxyprostaglandin E2; (5Z,11α,13E,15R,19R)-11,15,19-Trihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2 19(R)-isomer; 19(R)-Hydroxy-PGE2; Prostaglandin E2 19(R)-hydroxy derivative
EINECS	Contact for details

Quality Control

Our 19(R)-Hydroxy Prostaglandin E2 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and potency. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic and must be kept in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.