Description

α-Hydroxyetizolam is a key pharmaceutical intermediate and research chemical belonging to the thienodiazepine class. This compound is valued for its precise chemical structure, which is critical for the synthesis of advanced active pharmaceutical ingredients (APIs) and for investigative studies in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on neuropharmacology.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of specialized thienodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a reference standard or precursor in drug discovery programs targeting central nervous system (CNS) receptors.
• Analytical Reference Standard: Employed in quality control laboratories for method development, validation, and impurity profiling via HPLC, GC-MS, or NMR.
• Biochemical Research: Utilized in *in vitro* studies to investigate ligand-receptor interactions and metabolic pathways.
• Chemical Synthesis: Acts as a starting material or intermediate for the preparation of novel analogs in organic synthesis.

Basic Information

Product Name	α-Hydroxyetizolam
CAS No.	64546-10-7
Molecular Formula	C₁₇H₁₅ClN₂O₂S
Molecular Weight	346.83 g/mol
Synonyms	AH-ETZ; α-Hydroxyetizolam; 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-ol; Etizolam metabolite; Deschloroetizolam hydroxy analog
EINECS	Contact for details

Quality Control

Our α-Hydroxyetizolam is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.