Description

Glycoursodeoxycholic Acid is a conjugated bile acid derivative, formed by the amide linkage of ursodeoxycholic acid with glycine. This compound is of significant interest in pharmaceutical research and development due to its potential hepatoprotective and choleretic properties. It is primarily utilized by manufacturers in the pharmaceutical and life science sectors for the synthesis of advanced therapeutic agents and as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of novel therapeutic compounds targeting liver and metabolic disorders.
• Reference Standard: High-purity material used for quality control, method validation, and calibration in analytical chemistry (HPLC, LC-MS) within pharmaceutical and contract research organizations.
• Biochemical Research: Used in in vitro and in vivo studies to investigate bile acid metabolism, hepatocyte function, and cholestatic disease mechanisms.
• Active Pharmaceutical Ingredient (API) Development: Serves as a candidate molecule or precursor in the development of new APIs for treating primary biliary cholangitis (PBC) and other liver conditions.
• Cell Culture & Media Supplement: Employed in specialized cell culture applications to study bile acid transport and signaling pathways.

Basic Information

Product Name	Glycoursodeoxycholic Acid
CAS No.	64480-66-6
Molecular Formula	C₂₆H₄₃NO₅
Molecular Weight	449.63 g/mol
Synonyms	Glycoursodeoxycholic Acid; N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine; GUDCA; Glyco-ursodeoxycholic Acid; Ursodeoxycholylglycine; 3α,7β-Dihydroxy-5β-cholan-24-oylglycine
EINECS	Contact for details

Quality Control

Our Glycoursodeoxycholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Optical Rotation	Contact for details
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.