Description

16,16-Dimethyl-Delta2-Prostaglandin E1 is a synthetic analog of prostaglandin E1, a potent bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and targeted biological activity compared to its natural counterpart. It is primarily utilized in advanced pharmaceutical research and development, particularly in the study of vascular biology, inflammation, and cytoprotection.

Application

• Pharmaceutical Intermediates: Serves as a key synthetic building block for novel drug candidates targeting cardiovascular and inflammatory diseases.
• Biochemical Research: Used as a reference standard and active agent in studies of prostaglandin receptor (EP) signaling pathways and cellular responses.
• Vasodilation Studies: Applied in preclinical research to investigate mechanisms of blood vessel dilation and vascular tone regulation.
• Cytoprotective Agent Development: Explored for its potential to protect tissues from ischemic injury and promote healing in research models.
• Inflammation Modulation: Utilized in immunological research to study the modulation of inflammatory mediators and immune cell function.

Basic Information

Product Name	16,16-Dimethyl-Delta2-Prostaglandin E1
CAS No.	64318-77-0
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl-PGE1; 16,16-Dimethylprostaglandin E1; 16,16-Dimethyl-δ²-PGE1; Misoprostol Impurity C; 9-Oxo-11α,15α-dihydroxy-16,16-dimethyl-5-cis,13-trans-prostadienoic Acid; 5-cis,13-trans-16,16-Dimethylprosta-5,13-dien-1-oic-9-oxo-11α,15α-diol; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16,16-dimethylprosta-5,13-dien-1-oic Acid
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl-Delta2-Prostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.