Description

2,4-Difluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant industrial importance. Its unique structure, featuring both fluorine and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is essential for manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to introduce fluorine atoms to enhance product properties such as metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorobenzotrifluoride moiety contributes to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A valuable reagent in cross-coupling reactions and nucleophilic aromatic substitution for introducing fluorinated aryl groups.
• Electronic Chemicals: Used in the development of dielectric fluids and etching agents for the semiconductor industry.

Basic Information

Product Name	2,4-Difluorobenzotrifluoride
CAS No.	64248-61-9
Molecular Formula	C7H3F5
Molecular Weight	182.09 g/mol
Synonyms	1,3-Difluoro-4-(trifluoromethyl)benzene; 2,4-Difluoro-α,α,α-trifluorotoluene; 2,4-Difluoro(trifluoromethyl)benzene; α,α,α,2,4-Pentafluorotoluene; Benzene, 1,3-difluoro-4-(trifluoromethyl)-; 2,4-Difluorobenzyltrifluoride; (2,4-Difluorophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Density (at 20°C)	~1.45 g/mL
Refractive Index (n20D)	~1.40

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.