Description

2,6-Difluorobenzotrifluoride is a high-value fluorinated aromatic building block, essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs). Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant lipophilicity, metabolic stability, and electronic properties to target molecules. This compound is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluorobenzotrifluoride moiety contributes to biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed as a building block for electron-transport materials, semiconductors, and other components in OLEDs and organic photovoltaics.
• Specialty Polymers: Incorporated into high-performance polymers to enhance chemical resistance, thermal stability, and dielectric properties.
• Chemical Research & Development: A versatile reagent for introducing fluorine and trifluoromethyl groups in medicinal chemistry and material science research.

Basic Information

Item	Detail
Product Name	2,6-Difluorobenzotrifluoride
CAS No.	64248-60-8
Molecular Formula	C7H3F5
Molecular Weight	182.09 g/mol
Synonyms	1,3-Difluoro-2-(trifluoromethyl)benzene; 2,6-Difluoro-α,α,α-trifluorotoluene; 2,6-Difluorobenzylidene trifluoride; 2-(Trifluoromethyl)-1,3-difluorobenzene; α,α,α,2,6-Pentafluorotoluene; Benzene, 1,3-difluoro-2-(trifluoromethyl)-; 2,6-DFBTF
EINECS	Contact for details

Quality Control

Our 2,6-Difluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring reliable supply for critical process development and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.45 g/cm³
Boiling Point	~150-155°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.