Description

2,3-Difluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant industrial importance. Its unique structure, featuring both fluorine and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to develop novel compounds with enhanced properties such as metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms improve biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer & Material Science: Intermediate for creating specialty polymers, coatings, and electronic materials with specific dielectric and surface properties.
• Organic Synthesis: A valuable reagent in cross-coupling reactions and nucleophilic aromatic substitution for introducing fluorinated aryl groups.

Basic Information

Product Name	2,3-Difluorobenzotrifluoride
CAS No.	64248-59-5
Molecular Formula	C7H3F5
Molecular Weight	200.09 g/mol
Synonyms	1,2-Difluoro-3-(trifluoromethyl)benzene; 2,3-Difluoro-α,α,α-trifluorotoluene; 2,3-Difluoro(trifluoromethyl)benzene; 3-(Trifluoromethyl)-1,2-difluorobenzene; Benzene, 1,2-difluoro-3-(trifluoromethyl)-; α,α,α,2,3-Pentafluorotoluene
EINECS	Contact for details

Quality Control

Our 2,3-Difluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed at temperatures between 15-25°C to prevent evaporation and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.48 g/cm³
Boiling Point	~142-144 °C
Refractive Index (n20D)	~1.405 - 1.415

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.