Description

2-(Chlorosulfonyl)Benzoic Acid is a versatile and reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive sulfonyl chloride group and a carboxylic acid, makes it indispensable for creating complex molecular architectures. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, anticonvulsants, and carbonic anhydrase inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate sulfonylurea or sulfonamide moieties.
• Dyestuff and Pigment Manufacturing: Acts as a reactive intermediate for synthesizing sulfonated azo dyes and high-performance pigments.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups into polymers for enhanced properties or as a site for further chemical grafting.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic routes to sulfonated compounds.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes and catalysts in asymmetric synthesis.

Basic Information

Product Name	2-(Chlorosulfonyl)Benzoic Acid
CAS No.	63914-81-8
Molecular Formula	C7H5ClO4S
Molecular Weight	220.63 g/mol
Synonyms	2-Carboxybenzenesulfonyl chloride; o-Carboxybenzenesulfonyl chloride; Benzoic acid, 2-(chlorosulfonyl)-; 2-Chlorosulfonylbenzoic acid; o-(Chlorosulfonyl)benzoic acid; NSC 163081; 2-Sulfobenzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Chlorosulfonyl)Benzoic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent hydrolysis and degradation. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.