Description

Benzene, 1-(Difluoromethyl)-2-Fluoro- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role in introducing unique fluorine-containing motifs, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing difluoromethyl and fluoro substituents to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where fluorination can improve activity, selectivity, and environmental profile.
• Liquid Crystal Materials: Acts as a fluorinated core component in the synthesis of high-performance liquid crystals for display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials due to the influence of fluorine on electronic properties.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the synthesis of complex fluorinated architectures.
• Specialty Polymer Modifier: Can be incorporated as a monomer or additive to impart specific properties like chemical resistance or altered solubility to high-performance polymers.

Basic Information

Product Name	Benzene, 1-(Difluoromethyl)-2-Fluoro- (9Ci)
CAS No.	63878-70-6
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1-(Difluoromethyl)-2-fluorobenzene; 2-Fluoro-α,α-difluorotoluene; o-Fluoro-α,α-difluorotoluene; 2-Fluorobenzylidene difluoride; (2-Fluorophenyl)difluoromethane; Benzene, (difluoromethyl)fluoro-; 1-Fluoro-2-(difluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-(Difluoromethyl)-2-Fluoro- (9Ci) is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.