Description

Congocidine is a potent polyene antibiotic compound, also known as Netropsin, with significant biological activity. It is primarily valued for its high-affinity binding to the minor groove of double-stranded DNA, making it a critical tool in molecular biology and biochemical research. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for studies involving nucleic acid structure, gene regulation, and as a starting material for specialized diagnostic reagents.

Application

• Molecular Biology Research: Used as a specific DNA minor groove binder to study protein-DNA interactions, chromatin structure, and gene expression mechanisms.
• Biochemical Reagent: Serves as a key component in assays designed to investigate DNA conformation and stability.
• Pharmaceutical Intermediates: Acts as a precursor or reference standard in the development of novel therapeutic agents targeting genetic diseases.
• Diagnostic Development: Employed in the formulation of specialized kits and reagents for nucleic acid analysis and detection.
• Academic & Industrial R&D: A fundamental tool for universities, contract research organizations (CROs), and biotech companies engaged in fundamental life science research.

Basic Information

Product Name	Congocidine
CAS No.	63770-20-7
Molecular Formula	C₁₈H₂₆N₁₀O₄
Molecular Weight	446.47 g/mol
Synonyms	Netropsin; Netropsin dihydrochloride; Congocidine dihydrochloride; 2-[[4-[[(2-Amino-1-methyl-4,5-dihydro-1H-imidazol-5-yl)methylamino]methyl]pyrimidin-2-yl]amino]-N-(3-aminopropyl)acetamide; Distamycin A analog; Antibiotic M-6888; NSC 57153
EINECS	Contact for details

Quality Control

Our Congocidine is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' compliance needs in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Biological Activity	Confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.