Description

2,3-Dihydro-1,4-Benzodioxine-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile electrophilic reagent for introducing the 1,4-benzodioxinylsulfonyl moiety, enabling the construction of complex molecules with specific functional properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the benzodioxine scaffold for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology: Employed as a labeling or bioconjugation reagent for probing protein function or developing diagnostic tools.
• Dye and Pigment Manufacturing: Intermediate for creating specialized chromophores with enhanced light-fastness and color properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific sulfonamide or sulfonate functionalities.

Basic Information

Product Name	2,3-Dihydro-1,4-Benzodioxine-6-Sulfonyl Chloride
CAS No.	63758-12-3
Molecular Formula	C8H7ClO4S
Molecular Weight	234.66 g/mol
Synonyms	1,4-Benzodioxine-6-sulfonyl chloride, 2,3-dihydro-; 6-Chlorosulfonyl-2,3-dihydro-1,4-benzodioxine; 2,3-Dihydro-1,4-benzodioxin-6-sulfonyl chloride; 1,4-Benzodioxan-6-sulfonyl chloride; 6-(Chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine; Benzodioxane-6-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1,4-Benzodioxine-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.