Description

6,7-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methyl-8-Piperidinomorphinan CAS NO 63729-83-9 is a high-purity synthetic opioid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of more complex therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and academic research institutions engaged in neuropharmacology, analgesic development, and forensic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of specialized opioid-based active pharmaceutical ingredients (APIs) for research purposes.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, GC-MS, and other chromatographic analyses within pharmaceutical and forensic labs.
• Biochemical Research: Employed in in vitro studies to investigate opioid receptor binding, selectivity, and signal transduction pathways.
• Metabolite Studies: Serves as a precursor or analog for studying the metabolism and pharmacokinetics of related opioid compounds.
• Forensic Science: Utilized as a controlled substance analog for developing and validating detection assays in forensic toxicology.

Basic Information

Product Name	6,7-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methyl-8-Piperidinomorphinan
CAS No.	63729-83-9
Molecular Formula	C24H30N2O3
Molecular Weight	394.51 g/mol
Synonyms	8-Piperidinomorphinan derivative; 17-Methyl-4,5α-epoxy-3-methoxy-6,7-didehydro-8-piperidinomorphinan; 3-Methoxy-17-methyl-4,5α-epoxy-6,7-didehydro-8-piperidinomorphinan; 4,5α-Epoxy-3-methoxy-17-methyl-6,7-didehydro-8-piperidinomorphinan; Noroxymorphone piperidine analog; 8-Piperidino-oxymorphone analog
EINECS	Contact for details

Quality Control

Our 6,7-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methyl-8-Piperidinomorphinan is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation via IR and MS, and residual solvent analysis, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.