Description

Methyl 3-Chlorosulfonylbenzoate is a high-purity, versatile sulfonyl chloride derivative used as a key synthetic intermediate in advanced organic synthesis. This compound matters for its reactive chlorosulfonyl group, which enables the efficient introduction of sulfonamide or sulfonate functionalities into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide moieties with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the benzoate-sulfonyl chloride structure is integral.
• Functional Material Precursor: Serves as a monomer or modifying agent in the development of specialty polymers, dyes, and liquid crystals.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the creation of novel chemical entities for screening libraries.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Methyl 3-Chlorosulfonylbenzoate
CAS No.	63555-50-0
Molecular Formula	C8H7ClO4S
Molecular Weight	234.66 g/mol
Synonyms	3-(Chlorosulfonyl)benzoic acid methyl ester; Methyl 3-chlorosulfonylbenzoate; Benzoic acid, 3-(chlorosulfonyl)-, methyl ester; Methyl m-chlorosulfonylbenzoate; 3-Carbomethoxybenzenesulfonyl chloride; Methyl ester of 3-chlorosulfonylbenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Chlorosulfonylbenzoate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.