Description

p-Chlorosulfonyldihydrocinnamic Acid is a specialized aromatic sulfonyl chloride derivative, serving as a key synthetic intermediate in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an electrophilic sulfonyl chloride group and a carboxylic acid moiety for sequential derivatization. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require the incorporation of a chlorosulfonyl moiety.
• Chemical Research & Development: Serves as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups onto polymer backbones for subsequent cross-linking or property enhancement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom chemical synthesis services catering to the fine chemical industry.

Basic Information

Product Name	p-Chlorosulfonyldihydrocinnamic Acid
CAS No.	63545-54-0
Molecular Formula	C9H9ClO4S
Molecular Weight	248.68 g/mol
Synonyms	4-(Chlorosulfonyl)dihydrocinnamic Acid; 3-[4-(Chlorosulfonyl)phenyl]propanoic Acid; p-(Chlorosulfonyl)hydrocinnamic Acid; Benzenepropanoic acid, 4-(chlorosulfonyl)-; 4-Chlorosulfonylphenylpropionic Acid
EINECS	Contact for details

Quality Control

Our p-Chlorosulfonyldihydrocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and titration for assay confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.