Description

2-Amino-4-Chloro-3,5,6-Trifluoropyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring amino, chloro, and trifluoro substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-4-Chloro-3,5,6-Trifluoropyridine
CAS No.	63489-56-5
Molecular Formula	C5H2ClF3N2
Molecular Weight	182.53 g/mol
Synonyms	4-Chloro-3,5,6-trifluoropyridin-2-amine; 2-Amino-4-chloro-3,5,6-trifluoropyridine; 3,5,6-Trifluoro-4-chloropyridin-2-amine; 2-Pyridinamine, 4-chloro-3,5,6-trifluoro-; 4-Chloro-3,5,6-trifluoro-2-pyridinamine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Chloro-3,5,6-Trifluoropyridine is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your project specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.