Description

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]-6-Oxoheptanoic Acid is a high-purity synthetic prostaglandin intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of prostaglandin analogs, which are key therapeutic agents. It is primarily required by pharmaceutical manufacturers and advanced research institutions focused on developing treatments for cardiovascular, ocular, and inflammatory conditions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of prostaglandin E (PGE) and prostaglandin F (PGF) series analogs for therapeutic use.
• Ophthalmic Drug Development: Used in research and production of prostaglandin-based medications for glaucoma and ocular hypertension (e.g., Latanoprost, Travoprost analogs).
• Cardiovascular Research: Employed in the study and development of compounds affecting vasodilation and platelet aggregation.
• Inflammatory Pathway Studies: Serves as a standard or intermediate in biochemical research targeting cyclooxygenase pathways.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the commercial manufacturing of prostaglandin-based APIs.
• Reference Standard: Can be supplied as a high-purity analytical reference standard for quality control and method development.

Basic Information

Product Name	7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]-6-Oxoheptanoic Acid
CAS No.	63446-59-3
Molecular Formula	C20H32O6
Molecular Weight	368.47 g/mol
Synonyms	(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxooct-1-en-1-yl]cyclopentyl]-5-heptenoic Acid; 11-Deoxy-13,14-dihydro-15-keto-PGE1; 11-Deoxy-13,14-dihydro-15-keto-prostaglandin E1; DK-PGE1; 15-Keto-11-deoxy-13,14-dihydro-PGE1; 15-Ketoprostaglandin E1 derivative; Prostaglandin E1 Intermediate
EINECS	Contact for details

Quality Control

Our 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-Oxooct-1-Enyl]Cyclopentyl]-6-Oxoheptanoic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can supply material compliant with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, keep desiccated to protect from moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.