Description

(S)-n-Tosyl Amphetamine-D3 is a high-purity, isotopically labeled derivative of amphetamine, specifically designed for advanced analytical and research applications. This compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry, where it serves as a stable internal standard. It is primarily utilized by analytical laboratories, forensic science institutions, and pharmaceutical R&D departments engaged in method development, pharmacokinetic studies, and substance verification.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterated internal standard in LC-MS/MS and GC-MS methods for the precise quantification of amphetamine and related compounds in complex matrices.
• Forensic Analysis and Toxicology: Essential for developing and validating highly specific and sensitive assays for the detection and confirmation of controlled substances in biological samples.
• Pharmaceutical Research & Development: Supports drug metabolism and pharmacokinetic (DMPK) studies, aiding in the understanding of absorption, distribution, metabolism, and excretion (ADME) profiles.
• Reference Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments and ensuring the accuracy of test results in quality control laboratories.
• Clinical Research: Employed in clinical trials to monitor drug levels and metabolites in patient samples with high precision.
• Method Development and Validation: A key tool for scientists establishing new analytical protocols that require the highest level of specificity and minimal isotopic interference.

Basic Information

Product Name	(S)-n-Tosyl Amphetamine-D3
CAS No.	63386-42-5
Molecular Formula	C16H17D3NO2S
Molecular Weight	287.42 g/mol
Synonyms	(S)-1-Methyl-2-phenylethyl 4-methylbenzenesulfonate-d3; (S)-Amphetamine-d3 Tosylate; (S)-Deutero Amphetamine Tosylate; (S)-α-Methylbenzeneethanamine-d3 N-tosyl derivative; (S)-N-Tosylamphetamine-d3; (S)-Benzenemethanamine, α-methyl-N-[(4-methylphenyl)sulfonyl]-, α,α,β-d3-; d3-(S)-Tosylamphetamine
EINECS	Contact for details

Quality Control

Every batch of (S)-n-Tosyl Amphetamine-D3 is manufactured and analyzed under strict quality management systems to ensure exceptional purity and isotopic enrichment. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with the stringent requirements for analytical reference standards. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and identity confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.