Description

Glycerol-13C3 is a stable isotope-labeled analog of glycerol, where all three carbon atoms are the non-radioactive carbon-13 isotope. This high-purity compound is essential for advanced research and analytical applications requiring precise metabolic tracing and quantification. It is a critical reagent for scientists and industries focused on metabolic flux analysis, pharmaceutical development, and nutritional studies. The product is supplied under strict quality control to ensure isotopic enrichment and chemical purity for reliable experimental results.

Application

• Metabolic Research & Flux Analysis: Used as a tracer to study glycolysis, gluconeogenesis, and lipid biosynthesis pathways in cell cultures, tissues, and whole organisms.
• Pharmaceutical Development: Serves as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of glycerol and related metabolites in drug metabolism and pharmacokinetics (DMPK) studies.
• Nutritional Science: Employed in clinical and preclinical studies to investigate fat metabolism, energy expenditure, and the biochemical effects of diets and supplements.
• Biomarker Discovery & Validation: Acts as a critical standard in proteomic and metabolomic workflows to identify and validate disease biomarkers.
• Environmental & Microbiological Studies: Applied in research on microbial metabolism, biofuel production, and environmental biodegradation processes.
• NMR Spectroscopy: Utilized as a standard or tracer in Nuclear Magnetic Resonance (NMR) studies due to the distinct signal of the 13C-labeled atoms.

Basic Information

Product Name	Glycerol-13C3
CAS No.	63346-81-6
Molecular Formula	¹³C₃H₈O₃
Molecular Weight	95.09 g/mol
Synonyms	1,2,3-Propanetriol-13C3; Glycerin-13C3; Glycerine-13C3; 13C3-Glycerol; [13C3]-Glycerol; Trihydroxypropane-13C3; 1,2,3-Trihydroxypropane-13C3; Isotopic Glycerol
EINECS	Contact for details

Quality Control

Every batch of Glycerol-13C3 is manufactured and analyzed to meet exacting standards for isotopic enrichment and chemical purity. Our quality assurance protocol includes comprehensive testing via NMR, MS, and HPLC. A Certificate of Analysis (COA) is provided with each shipment, detailing the isotopic purity (atom % 13C), chemical purity, and results of identity confirmation tests. We adhere to cGMP principles for consistent production of high-value research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Ensure the container is sealed immediately after use to prevent absorption of atmospheric moisture, which could affect purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.