Description

4-Bromo-1-Naphthalenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the 4-bromo-1-naphthalenesulfonyl group to construct complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs), dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the naphthalene sulfonyl moiety imparts specific biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for creating sulfonated naphthalene dyes with enhanced color properties and solubility.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical characteristics.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and biochemical research due to its reactive sulfonyl chloride group.
• Cross-coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex structures.

Basic Information

Product Name	4-Bromo-1-Naphthalenesulfonyl Chloride
CAS No.	63279-36-7
Molecular Formula	C10H6BrClO2S
Molecular Weight	305.57 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 4-bromo-; 4-Bromo-1-naphthalenesulphonyl chloride; 4-Bromonaphthalene-1-sulfonyl chloride; 4-Bromo-1-naphthylsulfonyl chloride; 1-Naphthalenesulfonyl chloride, 4-bromo- (9CI); 4-Bromonaphthalenesulfonyl chloride; 4-Bromo-1-naphthalene sulfonyl chloride; NSC 403017
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Naphthalenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.