Description

Chlorodifluoroacetaldehyde Hydrate is a versatile fluorinated building block of significant importance in advanced organic synthesis. Its value lies in the introduction of the chlorodifluoromethyl group, a key motif for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and kinase modulators.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where fluorine substitution enhances bioavailability and environmental stability.
• Material Science Precursor: Used in the development of specialty polymers and coatings with unique surface properties.
• Fluorinated Liquid Crystal Research: Serves as a starting material for creating advanced fluorinated mesogens.
• Organic Synthesis Reagent: Employed in nucleophilic addition and condensation reactions to introduce the -CHClF2 moiety.
• Chemical Research & Development: Fundamental reagent in academic and industrial labs exploring new fluorination methodologies and C1 chemistry.

Basic Information

Product Name	Chlorodifluoroacetaldehyde Hydrate
CAS No.	63034-47-9
Molecular Formula	C2H3ClF2O2
Molecular Weight	132.49 g/mol
Synonyms	2-Chloro-2,2-difluoroacetaldehyde Hydrate; 2-Chloro-2,2-difluoroethanal Hydrate; Chlorodifluoroethanal Hydrate; Monochloro(difluoro)acetaldehyde Hydrate; Chlorodifluoroacetic aldehyde monohydrate; α,α-Difluoro-α-chloroacetaldehyde Hydrate; ClCF2CHO·H2O
EINECS	Contact for details

Quality Control

Our Chlorodifluoroacetaldehyde Hydrate is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and Karl Fischer titration, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 4.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.