Description

4-n-Propylbenzenesulfonyl Chloride is a versatile and reactive organosulfur compound used as a key sulfonylation reagent in organic synthesis. Its primary value lies in its ability to introduce the 4-n-propylbenzenesulfonyl (tosylate-like) protecting group or to act as an electrophile in the formation of sulfonamides and sulfonate esters. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and fine chemicals where specific sulfonyl functionalities are required.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that contain sulfonylurea or sulfonamide moieties.
• Chemical Research & Development: Employed as a specialized sulfonylation agent in academic and industrial R&D labs for novel compound library synthesis.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of certain sulfonated dyes and colorants.
• Polymer Chemistry: Can be utilized to modify polymers or as a monomer in the creation of specialty polymers with sulfone groups.
• Protecting Group Chemistry: Acts as a reagent for introducing a sulfonyl protecting group for alcohols and amines in multi-step synthetic sequences.

Basic Information

Product Name	4-n-Propylbenzenesulfonyl Chloride
CAS No.	63014-04-0
Molecular Formula	C9H11ClO2S
Molecular Weight	218.70 g/mol
Synonyms	4-Propylbenzenesulfonyl chloride; p-Propylbenzenesulfonyl chloride; 1-(Chlorosulfonyl)-4-propylbenzene; Benzenesulfonyl chloride, 4-propyl-; 4-n-Propylphenylsulfonyl chloride; p-n-Propylbenzenesulfonyl chloride; 63014-04-0; 4-Propylbenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-n-Propylbenzenesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.