Description

8-Fluoro-4-Hydroxyquinoline-3-Carboxylic Acid is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a hydroxyl group on the quinoline core, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance bioavailability and stability.
• Chemical Synthesis Building Block: Employed in organic chemistry for constructing complex heterocyclic compounds due to its reactive carboxylic acid and hydroxyl functional groups.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and functional organic materials with specific electronic or optical properties.
• Biochemical Research: Serves as a scaffold or probe in medicinal chemistry for studying enzyme inhibition and receptor-ligand interactions.

Basic Information

Product Name	8-Fluoro-4-Hydroxyquinoline-3-Carboxylic Acid
CAS No.	63010-70-8
Molecular Formula	C₁₀H₆FNO₃
Molecular Weight	207.16 g/mol
Synonyms	8-Fluoro-4-hydroxyquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 8-fluoro-4-hydroxy-; 8-Fluoro-4-hydroxy-3-quinolinecarboxylic acid; 4-Hydroxy-8-fluoroquinoline-3-carboxylic acid; 8-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 8-Fluoro-4-hydroxy-1H-quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Hydroxyquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is compatible with strong acids and organic solvents but should be kept away from incompatible materials. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.