Description

Staurosporine is a potent, cell-permeable alkaloid compound widely recognized as a broad-spectrum protein kinase inhibitor. Its primary value lies in its ability to induce apoptosis and serve as a critical research tool for studying intracellular signal transduction pathways. This high-purity biochemical is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for cancer research, neuroscience, and cell biology applications. Staurosporine CAS NO 62996-74-1 is supplied to meet the stringent demands of advanced laboratory and pre-clinical development work.

Application

• Biomedical Research: A fundamental tool for studying protein kinase function, signal transduction cascades, and mechanisms of programmed cell death (apoptosis).
• Oncology & Cancer Research: Used to investigate tumor cell proliferation, survival pathways, and to screen for novel anti-cancer therapeutics.
• Neuroscience Studies: Employed in models of neuronal cell death, neuroprotection, and the study of neurodegenerative diseases.
• Cell Biology & Biochemistry: Serves as a positive control in apoptosis assays (e.g., flow cytometry, caspase activation) and kinase inhibition studies.
• Pharmaceutical Development: Utilized in pre-clinical research for target validation and the development of kinase-targeted drugs.
• Academic & Industrial R&D: A standard reagent in laboratories focused on molecular biology, pharmacology, and drug discovery.

Basic Information

Product Name	Staurosporine
CAS No.	62996-74-1
Molecular Formula	C28H26N4O3
Molecular Weight	466.54 g/mol
Synonyms	Antibiotic AM-2282; STS; Staurosporin; AM-2282; Microbial Alkaloid CPP-1; (1S,2S,4R,5R,7S,8S,9S,11S)-4-Methoxy-9-methyl-2-[(methylamino)methyl]-12-oxa-4-azatetracyclo[7.4.0.02,7.05,11]trideca-3,6,13-triene-8,10-dione; NSC 623397
EINECS	Contact for details

Quality Control

Our Staurosporine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, impurity profile, and residual solvents. We adhere to high-purity research-grade standards, ensuring the product is suitable for sensitive biological and biochemical applications. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm
Biological Activity	Confirmed by cell-based assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.