Description

Prosta-5,13-Dien-1-Oic Acid,9,11,15-Trihydroxy-15-Methyl-,Methyl Ester,(5Z,9R,11R,13E,15S)- is a high-purity, stereochemically defined prostaglandin analog, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the development of targeted therapeutic agents, particularly in ophthalmology, cardiovascular research, and reproductive medicine. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in prostaglandin-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmology Research: Used in the development of novel treatments for glaucoma and ocular hypertension.
• Cardiovascular Research: Serves as a precursor for compounds studied for their effects on vasodilation and platelet aggregation.
• Reproductive Medicine: Employed in the research and synthesis of agents related to fertility and parturition.
• Biochemical Research: Acts as a reference standard and a tool compound for studying prostaglandin receptors and signaling pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for introducing complex, biologically active prostaglandin scaffolds.

Basic Information

Product Name	Prosta-5,13-Dien-1-Oic Acid,9,11,15-Trihydroxy-15-Methyl-,Methyl Ester,(5Z,9R,11R,13E,15S)-
CAS No.	62776-96-9
Molecular Formula	C22H36O6
Molecular Weight	396.52 g/mol
Synonyms	15(S)-15-Methyl Prostaglandin E2 Methyl Ester; 15(S)-15-Methyl PGE2 Methyl Ester; Methyl (5Z,9R,11R,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oate; 15-Methyl PGE2 ME; (15S)-15-Methylprostaglandin E2 Methyl Ester; 15(S)-Me-PGE2 Methyl Ester; Prostaglandin E2 15-Methyl Methyl Ester (15S-isomer)
EINECS	Contact for details

Quality Control

Our production of Prosta-5,13-Dien-1-Oic Acid,9,11,15-Trihydroxy-15-Methyl-,Methyl Ester adheres to stringent quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including chiral HPLC for stereochemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to ensure compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (5Z,9R,11R,13E,15S)-isomer
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.