Description

Nojirimycin-1-Sulfonic Acid is a chemically modified derivative of the natural product nojirimycin, characterized by the introduction of a sulfonic acid group. This modification significantly enhances its water solubility and alters its biological activity profile, making it a valuable intermediate and research tool. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of glycosidase inhibitors and novel therapeutic agents.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthesis of novel glycosidase inhibitors for potential therapeutic applications.
• Biochemical Probe: Used in enzymatic studies to investigate the mechanism and inhibition of α-glucosidases and other carbohydrate-processing enzymes.
• Lead Compound Development: Serves as a structural scaffold for medicinal chemistry programs aimed at developing treatments for diabetes, viral infections, and lysosomal storage disorders.
• Academic & Institutional Research: Employed in life science laboratories for fundamental research on carbohydrate metabolism and glycobiology.
• Reference Standard: Used as a high-purity analytical standard in quality control and method development for related compounds.

Basic Information

Product Name	Nojirimycin-1-Sulfonic Acid
CAS No.	62770-70-1
Molecular Formula	C6H13NO8S
Molecular Weight	259.24 g/mol
Synonyms	1-Deoxynojirimycin-1-sulfonic acid; DNS; 1-Deoxynojirimycin sulfonate; Nojirimycin 1-sulfonate; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol 1-sulfonic acid; 5-Amino-5-deoxy-D-glucopyranose 1-sulfonic acid; D-Glucose, 5-amino-5-deoxy-, 1-sulfate
EINECS	Contact for details

Quality Control

Our Nojirimycin-1-Sulfonic Acid is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.