Description

5,6Beta-Dihydro Pgi2 CAS NO 62770-50-7 is a stable synthetic analog of prostacyclin (PGI2), a potent vasodilator and platelet aggregation inhibitor. This compound is valued for its enhanced chemical stability compared to the parent molecule, making it a crucial intermediate and reference standard in cardiovascular and thrombosis research. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on developing novel therapeutic agents for hypertension, pulmonary arterial hypertension (PAH), and other vascular disorders.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in drug development.
• Biochemical Research: Serves as a key tool compound for studying prostacyclin receptor (IP receptor) signaling pathways and mechanisms of vasodilation.
• Cardiovascular Drug Discovery: Acts as a critical intermediate in the synthesis of novel prostacyclin analogs for therapeutic applications.
• Platelet Function Studies: Employed in *in vitro* assays to investigate antiplatelet activity and mechanisms of thrombosis prevention.
• Academic Research: Utilized in university and institutional labs for fundamental pharmacological and physiological studies.

Basic Information

Product Name	5,6Beta-Dihydro Pgi2
CAS No.	62770-50-7
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5,6-Dihydroprostacyclin; 5,6-Dihydro PGI2; 15(S)-15-Methyl-9-deoxy-9α,11α-epoxyprostaglandin F1α; 9-Deoxy-9α,11α-epoxy-15-hydroxy-15-methylprosta-5Z,13E-dien-1-oic acid; Carbacyclin derivative; Stable prostacyclin analog; Iloprost intermediate
EINECS	Contact for details

Quality Control

Our 5,6Beta-Dihydro Pgi2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.