Description

R(+)-SKF-38393 Hydrochloride is a potent and selective dopamine D1 receptor agonist, a key pharmacological tool in neuroscience research. Its high purity and well-defined activity make it essential for studying dopaminergic pathways, receptor function, and related neurological disorders. This compound is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on CNS drug discovery and neuropharmacology.

Application

• Neuroscience Research: A standard reference agonist for investigating dopamine D1 receptor signaling and function in vitro and in vivo.
• Pharmacological Studies: Used to elucidate the role of D1 receptors in behaviors such as locomotion, reward, and cognition.
• Drug Discovery & Development: Serves as a critical tool compound for screening and validating new therapeutic candidates targeting the dopaminergic system.
• Biochemical Assays: Employed in receptor binding assays, functional cellular assays (e.g., cAMP accumulation), and signal transduction pathway analysis.
• Academic & Clinical Research: Supports fundamental research into neurological and psychiatric conditions like Parkinson's disease, schizophrenia, and addiction.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in related research.

Basic Information

Product Name	R(+)-SKF-38393 Hydrochloride
CAS No.	62751-59-1
Molecular Formula	C17H19ClN2O2
Molecular Weight	318.80 g/mol
Synonyms	R(+)-SKF-38393 HCl; (R)-(+)-1-Phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol Hydrochloride; (R)-(+)-SKF-38393 Hydrochloride; R(+)-1-Phenyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride; SKF 38393 R(+)-isomer hydrochloride; Dopamine D1 receptor agonist (R)-(+)-form hydrochloride
EINECS	Contact for details

Quality Control

Our R(+)-SKF-38393 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation (IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.