Description

1,2-Bis(Bromomethyl)-3-Fluorobenzene is a versatile and highly reactive fluorinated aromatic building block. This compound is valued for its ability to introduce both bromomethyl and fluorine functionalities in a single step, enabling efficient synthesis of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorine atom enhances biological activity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel phosphine ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research & Development: A valuable reagent for constructing complex heterocycles and functionalized aromatic systems in academic and industrial R&D settings.
• Fluorine Chemistry Studies: Used as a model substrate to study nucleophilic substitution reactions and the influence of fluorine on neighboring group reactivity.

Basic Information

Product Name	1,2-Bis(Bromomethyl)-3-Fluorobenzene
CAS No.	62590-16-3
Molecular Formula	C8H7Br2F
Molecular Weight	281.95 g/mol
Synonyms	3-Fluoro-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-3-fluorobenzene; 3-Fluorobenzene-1,2-diyldimethanol, dibromide; 3-Fluoro-o-xylene-α,α'-dibromide; α,α'-Dibromo-3-fluoro-o-xylene; 1,2-Bis(bromomethyl)-3-fluoro-benzene; 3-Fluoro-1,2-bis(bromomethyl)benzene; 2-Fluoro-1,3-bis(bromomethyl)benzene (isomer)
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Bromomethyl)-3-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.