Description

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,S)-3-Hydroxy-3-Methyl-5-Phenyl-1-Penten-4-Ynyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant synthetic importance. This compound serves as a critical building block in the synthesis of complex prostaglandin analogs and other bioactive molecules. It is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical industries, where precise stereochemistry and high purity are paramount for successful outcomes.

Application

• Key Intermediate in Prostaglandin Synthesis: A vital precursor for the production of prostaglandin E (PGE) and F (PGF) series analogs, which have diverse therapeutic applications.
• Pharmaceutical R&D: Used in medicinal chemistry research for developing new drug candidates targeting inflammation, cardiovascular conditions, and reproductive health.
• Fine Chemical Manufacturing: Employed in multi-step organic synthesis to construct complex molecular architectures with specific biological activity.
• Biochemical Research: Serves as a reference standard or tool compound in studies investigating prostaglandin receptor interactions and signaling pathways.
• Process Development: Utilized for scaling up and optimizing synthetic routes for prostaglandin-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,S)-3-Hydroxy-3-Methyl-5-Phenyl-1-Penten-4-Ynyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester
CAS No.	62475-37-0
Molecular Formula	C25H32O5
Molecular Weight	412.52 g/mol
Synonyms	Methyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyl-5-phenylpent-1-en-4-yn-1-yl]cyclopentyl]hept-5-enoate; Prostaglandin F2α Methyl Ester Intermediate; 11-Deoxy-16-phenoxy-17,18,19,20-tetranor-PGF2α Methyl Ester; PGF2α Analogue Intermediate; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyl-5-phenylpent-1-en-4-yn-1-yl]cyclopentyl]-5-heptenoic acid methyl ester; 62475-37-0; Latanoprost Related Compound; Prostanoid Intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.