Description

(5Z,13E,15S)-2,2-Difluoro-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,9-Lactone is a high-purity, synthetic prostaglandin analog. This compound is valued for its potent biological activity and serves as a critical advanced pharmaceutical intermediate in the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for producing targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prostaglandin-based drug candidates targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard and active compound in pharmacological studies and biological pathway analysis.
• Ophthalmic Drug Development: Potential precursor in the research of treatments for conditions like glaucoma, due to the activity profile of related prostaglandin analogs.
• Chemical Synthesis: Serves as a specialized synthon in complex organic synthesis for introducing the prostaglandin core structure.
• Cell Signaling Studies: Utilized in laboratory research to investigate the role of prostaglandin receptors and related cellular mechanisms.

Basic Information

Product Name	(5Z,13E,15S)-2,2-Difluoro-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,9-Lactone
CAS No.	62443-67-8
Molecular Formula	C21H28F2O5
Molecular Weight	398.45 g/mol
Synonyms	2,2-Difluoro-9α,11α,15-trihydroxy-15-methylprosta-5,13-dien-1-oic acid 1,9-lactone; 15-Methyl-2,2-difluoro PGF2α 1,9-lactone; Travoprost Lactone Intermediate; Fluprostenol Lactone Analog; AL-6221 Lactone; Prostaglandin F2α 15-methyl-2,2-difluoro analog lactone; (5Z,13E,15S)-15-Methyl-2,2-difluoro-9α,11α,15-trihydroxyprosta-5,13-dien-1-oic acid γ-lactone
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-2,2-Difluoro-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,9-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.