Description

(5Z,13E,15S)-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,15-Lactone is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. Its precise stereochemistry and lactone structure make it a critical building block for synthesizing bioactive molecules targeting specific physiological pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing novel therapeutics in areas such as ophthalmology, cardiovascular medicine, and reproductive health.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potent prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in the development of prostaglandin analogs for glaucoma treatment and other intraocular pressure disorders.
• Biochemical Research: Acts as a reference standard and tool compound for studying prostaglandin receptors, signal transduction, and related metabolic pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for complex, stereospecific organic molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP and non-GMP production campaigns.

Basic Information

Product Name	(5Z,13E,15S)-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,15-Lactone
CAS No.	62411-21-6
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	15(S)-15-Methyl-PGF2α 1,15-Lactone; 15-Methylprostaglandin F2α 1,15-Lactone; 9α,11α,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid, 1,15-lactone; Latanoprost Related Compound C; (5Z,13E)-(9R,11R,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid γ-lactone; 15-Methyl-PGF2α γ-lactone; Prostaglandin F2α 15-methyl 1,15-lactone
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-9α,11α,15-Trihydroxy-15-Methylprosta-5,13-Dien-1-Oic Acid 1,15-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with full traceability are provided with every shipment. We support development projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic and light-sensitive; allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, maintain the recommended cold chain.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.