Description

(5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,15-Lactone is a high-purity synthetic prostaglandin derivative, specifically a lactone form of 15(S)-15-methyl-PGA2. This compound matters as a critical advanced pharmaceutical intermediate and a versatile chemical building block for research into prostaglandin-related biological pathways. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic research institutions focused on developing novel therapeutics and studying inflammation, smooth muscle contraction, and other physiological processes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of prostaglandin-based drugs and analogs.
• Biochemical Research: Used as a reference standard and active compound in studies of prostaglandin receptors (EP, FP) and their signaling mechanisms.
• Cell Culture & In Vitro Studies: Applied in research models to investigate effects on cell proliferation, inflammation, and apoptosis.
• Fine Chemical Synthesis: Serves as a sophisticated starting material or building block for the synthesis of more complex, biologically active molecules.
• Ophthalmic Research: Investigated for potential applications related to intraocular pressure and ocular therapeutics.
• Standards & Calibration: High-purity material for use as an analytical standard in HPLC, LC-MS, and other quality control methods.

Basic Information

Product Name	(5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,15-Lactone
CAS No.	62410-98-4
Molecular Formula	C20H28O5
Molecular Weight	348.44 g/mol
Synonyms	15(S)-15-Methyl-PGA2 Lactone; 9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid, 1,15-lactone, (5Z,13E,15S)-; 15-Methyl-PGA2 Lactone; 15(S)-15-Methyl-prostaglandin A2 Lactone; 11-Deoxy-15(S)-15-methyl-PGE2 Lactone; PGA2 Methyl Lactone Derivative; (5Z,13E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic Acid γ-Lactone
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,15-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.