Description

(5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,9-Lactone is a high-purity synthetic prostaglandin derivative, specifically a lactone form of a key metabolic intermediate. This compound is of significant value for advanced pharmaceutical research and development, particularly in the study of prostanoid signaling pathways and inflammation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality biochemical tools for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex prostaglandin-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a key reagent in studying prostanoid receptors, enzyme inhibition, and inflammatory mediators.
• Cell Signaling Studies: Applied in vitro to investigate the role of specific prostaglandin metabolites in cellular processes and signal transduction pathways.
• Analytical Standard: Serves as a certified reference material (CRM) for method development and quality control in analytical laboratories using HPLC, LC-MS, or GC-MS.
• Fine Chemical Synthesis: Utilized as a sophisticated chiral synthon for the preparation of other specialized prostaglandin analogs and derivatives.

Basic Information

Product Name	(5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,9-Lactone
CAS No.	62410-77-9
Molecular Formula	C₂₀H₂₈O₅
Molecular Weight	348.44 g/mol
Synonyms	9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid 1,9-lactone; 11-Oxo-9α,15-dihydroxyprosta-5,13-dien-1-oic acid γ-lactone; 9-Deoxy-9α,11α-epoxy-15-hydroxy-5-cis-13-trans-prostadienoic acid; Prostaglandin D2 Lactone; PGD2 Lactone; 11-Keto-PGD2 Lactone; (5Z,13E)-(9S,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oate 1,9-lactone
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-9α,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid 1,9-Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep the primary container sealed within a secondary protective barrier.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.