Description

Benzenesulfonyl Chloride, 4-(Acetylamino)-2-Methyl- (9Ci) is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functional groups, which enable it to act as a versatile sulfonylation and amidation reagent for constructing complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the sulfonyl moiety is integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing specialized azo dyes and colorants with enhanced properties.
• Polymer Chemistry: Employed as a modifying agent or cross-linking monomer to introduce sulfonamide functional groups into polymer chains.
• Chemical Research & Development: A valuable reagent for method development and creating custom chemical libraries in medicinal chemistry.
• Peptide Modification: Used to selectively modify amino acid side chains, such as lysine, to alter peptide properties.

Basic Information

Product Name	Benzenesulfonyl Chloride, 4-(Acetylamino)-2-Methyl- (9Ci)
CAS No.	62374-67-8
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	4-Acetamido-2-methylbenzenesulfonyl chloride; N-[2-Methyl-4-(chlorosulfonyl)phenyl]acetamide; 2-Methyl-4-acetamidobenzenesulfonyl chloride; 4-(Acetylamino)-2-methylbenzenesulfonyl chloride; p-Acetamido-o-toluenesulfonyl chloride; 4-Acetamido-o-toluenesulfonyl chloride; NSC 403119
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl Chloride, 4-(Acetylamino)-2-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.