Description

3-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the sulfonyl chloride and the bromo substituent—which enable precise, sequential functionalization for creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for creating specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Cross-Coupling Reactions: The bromoaryl group facilitates participation in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Sulfonylation Agent: Used to introduce the sulfonyl moiety into target molecules to alter solubility, bioavailability, or biological activity.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	62202-40-8
Molecular Formula	C7H3BrClF3O2S
Molecular Weight	323.51 g/mol
Synonyms	3-Bromo-α,α,α-trifluoro-p-toluenesulfonyl chloride; 4-(Trifluoromethyl)-3-bromobenzenesulfonyl chloride; 2-Bromo-α,α,α-trifluoro-4-toluenesulfonyl chloride; Benzenesulfonyl chloride, 3-bromo-4-(trifluoromethyl)-; 3-Bromo-4-trifluoromethylbenzenesulfonyl chloride; 3-Bromo-4-(trifluoromethyl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.