Description

(5Z,9α,11α,13E,15S)-9,15-Di(Acetyloxy)-11-Hydroxyprosta-5,13-Dien-1-Oic Acid Methyl Ester is a synthetic prostaglandin analog, a key intermediate in the production of advanced pharmaceutical compounds. This high-purity intermediate is critical for ensuring the efficacy and consistency of final active pharmaceutical ingredients (APIs) in therapeutic applications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and synthesis of prostaglandin-based drugs, particularly for cardiovascular and ophthalmic treatments.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of prostaglandin-based Active Pharmaceutical Ingredients (APIs).
• Cardiovascular Research: Used in the development of compounds targeting vasodilation and platelet aggregation for cardiovascular therapies.
• Ophthalmic Drug Development: Serves as a precursor in the synthesis of prostaglandin analogs used to treat glaucoma and ocular hypertension.
• Biochemical Research: Employed as a reference standard and a tool compound in pharmacological studies to understand prostaglandin receptor activity and signaling pathways.
• Process Development & Scale-Up: Used by process chemists to optimize synthetic routes for commercial-scale manufacturing of prostaglandin drugs.

Basic Information

Product Name	(5Z,9α,11α,13E,15S)-9,15-Di(Acetyloxy)-11-Hydroxyprosta-5,13-Dien-1-Oic Acid Methyl Ester
CAS No.	62158-37-6
Molecular Formula	C25H38O7
Molecular Weight	450.57 g/mol
Synonyms	9,15-Di-O-acetyl-11-hydroxyprosta-5,13-dien-1-oic acid methyl ester; Methyl 9,15-diacetyl-11-hydroxyprosta-5,13-dien-1-oate; Prostaglandin F2α methyl ester diacetate; 11-Hydroxy-9,15-diacetoxyprosta-5,13-dien-1-oic acid methyl ester; PGF2α methyl ester diacetate; 9α,15α-Diacetoxy-11β-hydroxy-5-cis,13-trans-prostadienoic acid methyl ester; Latanoprost intermediate
EINECS	Contact for details

Quality Control

Our (5Z,9α,11α,13E,15S)-9,15-Di(Acetyloxy)-11-Hydroxyprosta-5,13-Dien-1-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.